ZP123 REDUCES ENERGY REQUIRED FOR DEFIBRILLATION BY PREVENTING CONNEXIN43 REMODELING DURING PROLONGE

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：woai6672690

【摘要】

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【作者】

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Yi Shao-lei Zhang Jing Su Guo-ying Li Jing-sha Liu Hong-zhen Zhang Yun Zhong Jing-quan

【机构】

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Department of Cardiology,Qilu Hospital,Shandong University

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

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Objectives In ventricular fibrillation, the uncoupling of gap junctions slows conduction velocity and increases action-potential dispersion, which slows and diminishes defibrillation.We studied how the peptide ZP123, a gap-junction enhancer, might lower defibrillation-energy requirements.

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ZP123 REDUCES ENERGY REQUIRED FOR DEFIBRILLATION BY PREVENTING CONNEXIN43 REMODELING DURING PROLONGE

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