Role of LOX-1 in pulmonary vascular remodeling in rats with hypoxia induced pulmonary arterial hyper

• 作 者: WeifangZHANG;ChangpingHU;
• 机 构: Department of Pharmacology,School of Pharmaceutical Sciences,Central South University,Changsha 41007
• 出 处: 中国生理学会第24届全国会员代表大会暨生理学学术大会
• 发表日期: 2014年期

　　Aim:To investigate the role of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in pulmonary vascular remodeling in rats with hypoxia-induced pulmonary arterial hypertension (PAH) and the underlying mechanisms.Methods:SD rats were maintained under hypoxia (10 %O2) for 3 weeks to induce PAH.