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In this study, we have determined the contents and distribution of Zn and Cd in the surface sediments from Prydz Bay, Antarctica.The main sources of the trace elements and their geographic heterogeneity, and the relation between Zn and Cd have been discussed on the basis of Cluster Analysis, Principle Component Analysis, and calculation of biogenic and lithogenic inputs.The results show that the contents of trace metals range from 34.6 mg kg-1 to 96.6 mg kg-1 for Zn, and from 0.254 mg kg-1 to 0.441 mg kg-1 for Cd, respectively.No significant anthropogenic effect is observed according to the enrichment factor.Biogenic and lithogenic inputs are the main sources of trace metals.They are almost equal for Zn and Cd at the AIS edge, while the continental shelf and deep ocean are dominated by biogenic input and its proportion is much higher for Zn than for Cd.Lithogenic Zn and Cd are strongly positive correlated in the sediment, while the relation between biogenic Zn and Cd is much more complicated.