Background: Treatment of traumatic painful neuromas remains a challenge despite advances in surgical options and the mechanism of neuroma-associated pain is not yet fully understood.Objective: We focu
Bone callus,generated during fracture healing,is commonly discarded during surgical procedures.The aim of this study was to investigate the osteogenic potential of bone callus and its possible use as
Osteosarcoma is the most common malignant bone tumor.In most cases,it occurs in young patients under 20 years.Osteosarcoma cells proliferate rapidly and tend to invade other body tissues.At present,ne
Excessive activated osteoclast may lead to bone mass loss.The flavonoid compounds extracted from herbal medicine have been report to inhibit osteoclastogenesis.Galangin is a natural bioflavonoid,and i
Osteosarcoma is the most common malignant bone tumor and frequently affects adolescents,with tumor cells tending to proliferation and invasion.Neoadjuvant chemotherapy currently is the primary strateg
Osteoporosis is characterized by systematic reduced bone mass result from dysregulated bone metabolism where activated bone resorption activities exceed bone formation activities.Nephronectin (NPNT) i
Background Roxadustat (FG-4592) is a specific hypoxia-inducible factor 1α (HIF-1α) prolyl hydroxylase inhibitor.We investigated the effects of the Pharmacological delay with FG-4592 on the survival an