Insights into the mechanism of Huangqi decoction(HQD)by means of metabolomics and network pharmacolo

来源 :2019中国化学会第十五届全国计算(机)化学学术会议 | 被引量 : 0次 | 上传用户:guangtoucx
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Huangqi decoction(HQD)consists of Radix Astragali(RA)and Radix Glycyrrhizae(RG)in a ratio of 6:1,which has been used to treat liver fibrosis for many years.
其他文献
“Molecular scaffold” is one of the most important and widely used concept in medicinal chemistry.
阿片类药物在镇痛药市场中一直占据着主要的份额,其镇痛活性优于其他镇痛药,因此在麻醉和医疗方面有极为普遍的使用,其中芬太尼类化合物活性强相对安全性也较高。
Hepatotoxicity is a major cause of drug withdrawal from the market.To reduce the drug attrition induced by hepatotoxicity,an accurate and efficient hepatotoxicity prediction system must be constructed
大环化合物的发现犹如一缕春风拂过药物化学领域,大环药物研究应运而生,并逐渐遍地生花。迄今为止,已有超过100种大环药物处于上市或在研阶段[1]。
Cyclooxygenase-2(COX-2)is an inducible form of the COX enzyme,and is an important target of Nonsteroidal Anti-Inflammatory Drugs(NSAIDs).
The solvation structure and dynamics of organic molecules at liquid-solid interfaces have great implications in chromatography and heterogeneous catalysis.
MCR-ALS(多元曲线分辨-交替最小二乘)作为一种双线性方法在过去的二十年中发挥了重要的作用,能够帮助研究者在复杂体系分析中获取具有理化意义的信息,取得体系中主成分的纯信号及其相对贡献或浓度。
HIV-1 protease inhibitors(PIs)make a vital contribution on highly active antiretroviral therapy(HAART)of human immunodeficiency virus(HIV).
The increasing prevalence of fungal diseases,continual development of resistance,and stringent environmental regulations have revealed an urgent need to develop more selective,safer,resistance-breakin
Fragment-based drug design(FBDD)is a promising methodology to find quality drug leads.It is important in the curriculum of a drug design course due to its impact on drug discovery.