C-Myc is involved in UUO-induced renal fibrosis via upregulating integrin αV

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：ybws2006

【摘要】

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【作者】

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Limin Lu

【机构】

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Department of Physiology and Pathophysiology,Shanghai Medical College,Fudan University,Shanghai,2000

【出处】

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2016年国际生理学学术大会

【发表日期】

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2016年6期

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　　Renal fibrosis is a common feature of all forms of chronic kidney disease(CKD).C-Myc,a pleiotropic transcriptional factor,was elevated in the kidney of unilateral ureteral obstruction(UUO)mice.The experiments were aimed to investigate the role of c-Myc in renal fibrosis and its related downstream pathway.

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C-Myc is involved in UUO-induced renal fibrosis via upregulating integrin αV

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