Biomimetic polymers responsive to a biological signaling molecule: nitric oxide (NO) triggered rever

• 作 者: JinmingHu[1]MichaelR.Whittaker[1]HienDuong[2]YangLi[1]CyrilleBoyer[2]ThomasP.Davis[1]
• 机 构: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology,Monash Institute of Pharmaceu
• 出 处: The Third Symposium on Innovative Polymers for Controlled De
• 发表日期: 2014年期

　　Nitric oxide (NO),known as an atmospheric pollutant and a potential health hazard,is recognized as an endothelium-derived relaxing factor (EDRF) and a broad-spectrum biological signaling molecule operating at both systemic and specific cellular levels [1-3].Herein,novel nitric oxide (NO)-responsive monomers (NAPMA and APUEMA),containing o-phenylenediamine functional groups,have been polymerized to form NO responsive macromolecular chains as truly biomimetic polymers.