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目的探讨慢性HBV感染者对干扰素抗病毒疗效反应差异与KIR基因型的相关性。方法对56例慢性HBV染α-干扰素有效应答者(实验1组)和57例慢性HBV感干扰素无应答或部分应答者(实验2组)分别进行KIR基分型检测,按文献划分基因型和单体型,比较两组间KIR基因型及单倍型的差异。结果AH基因
Objective To investigate the relationship between the response to interferon antiviral therapy and KIR genotype in patients with chronic HBV infection. Methods KIR genotyping was performed on 56 patients with effective response to chronic HBV infection (group 1) and 57 patients with no or partial response to chronic HBV infection (group 2) Type and haplotype, KIR genotypes and haplotype differences between the two groups were compared. Results AH gene