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Background: Qigong is a kind of traditional Chinese exercise combining breathing,movement,and meditation in order to keep fit for the purpose of preventing disease and prolonging life.Methods: Within this short article some topics like clinical efficacy and mechanism of health-care Qigong,the impact on the respiratory function and on the cardiovascular function,the influence on the immune system,the impact on the emotional aspects and brain function research on Qigong will be discussed briefly.Results: Light imagination during meditation showed a 22.2%increase of the mean blood flow velocity in the posterior cerebral artery and a mean reduction of blood flow velocity of 23.1%in the middle cerebral artery in a male Qigong master.Conclusions: In summary,the clinical efficacy of Qigong cannot be denied.Health-care Qigong exercise may prevent diseases however more scientific studies with high quality are also needed.