Design,Synthesis and Evaluation of Novel Trimethylpyrazine-2-carbonyloxy-cinnamic Acid Esters as Pot

来源 :第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 | 被引量 : 0次 | 上传用户：watermb

【摘要】

：

【作者】

：

Hongfei Chen Peng Zhan Xinyong Liu

【机构】

：

School of Pharmaceutical Sciences,Shandong University,No.44,Wenhuaxi Road,Jinan 250012

【出处】

：

第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会

【发表日期】

：

2012年8期

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　　Ligustrazine(tetramethyl pyrazine,TMP,a major effective component of Chinese traditional herbal medicine Chuanxiong,has been reported to be a multifunctional drug in the treatment of cardiovascular diseases(CVDs),with pharmacological activities such as anti-platelet aggregation,free radical scavenge effect and protection against endothelial cells injury1,2.Nowadays ligustrazine is widely used in China for CVDs therapies.

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Design,Synthesis and Evaluation of Novel Trimethylpyrazine-2-carbonyloxy-cinnamic Acid Esters as Pot

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