【摘 要】
：
Object is to present the outcome and long-term follow-up of 12 patients with primary hereditary dystonia treated by deep brain stimulation (DBS) of the internal pallidum (GPi).Nine of the 12 patients
【机 构】
：
Department of Neurology Tokyo Metropolitan Neurological Hospital Japan
论文部分内容阅读
Object is to present the outcome and long-term follow-up of 12 patients with primary hereditary dystonia treated by deep brain stimulation (DBS) of the internal pallidum (GPi).Nine of the 12 patients were positive for DYT1, two patients were siblings and negative for DYT1, and one patient was positive for DYT3.Eleven patients had generalized dystonia, excluding a girl negative for DYT1 who had postural hand tremor and focal dystonia.Bilateral GPi DBS was performed in all the patients, and the follow-up period ranged from 24 to 100 months.All the patients were evaluated using the Burke-Fahn-Marsden dystonia score (BFMDS) before and after starting DBS stimulation.
其他文献
The rapid developments in mouse neuro-genetics, particularly with regards to the generation of genetic mouse models of human brain disorders, have opened up important new opportunities for the investi
Neurodegenerative diseases cause damage to several neuromodulatory brain regions that play a key role in learning and plasticity.Identifying the basic mechanisms by which these neuromodulators affect
In order to understand healthy and pathological human brain development and function, we also have to better understand the underlying brain networks and brain rhythms, to understand how brain areas a
Our EEG-and-Psychological-Response system is being developed at Lake Forest College for teaching scientific research and for medical diagnosis where large-scale electronic installations are impractica
Electromyography (EMG) is useful in investigating muscle activation; however, noninvasive evaluation of the raw surface EMG with voluntary muscle contraction has been limited due to its complicated wa
I talk about how to obtain noninvasively biomechanical properties of the brain and the intracranial condition using magnetic resonance imaging (MRI), and how to apply those in clinical.I first show an
Several studies show that some pathologies (schizophrenia, Alzheimer disease...) are associated with re-arrangements in active connections between structures, which may result in impaired functional n
Background and purpose-To investigate feasibility and usefulness of contrast enhanced MR angiography (CEMRA) imaging protocol to follow up patients with intracranial aneurysms treated with endovascula
Visual hallucinations (VHs) are common in Lewy body disease (LBD) with dementia, including dementia with Lewy bodies and Parkinsons disease with dementia, while auditory hallucinations are quite rare.
An innovative absolute intracranial pressure (aICP) measurement technology has been proposed (US, EU and Japan patents) which does not need a calibration of the system "individual patient-noninvasive