【摘 要】
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Objectives There is an age-related decline in mesenchymal stem cells (MSCs) functions and old age have a negative effect on MSCs ageing and proliferation.To investigate the role of SIRT1, a NAD+ depen
【机 构】
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Cardiovascular Key Lab of Zhejiang Province,The Second Affiliated Hospital,School of Medicine,Zhejia
【出 处】
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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int
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Objectives There is an age-related decline in mesenchymal stem cells (MSCs) functions and old age have a negative effect on MSCs ageing and proliferation.To investigate the role of SIRT1, a NAD+ dependent histone deacetylase, in old sourced MSCs senescence and proliferation,we examined the effects of Sirt1 manipulation in Old sourced MSCs.
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