• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Interactions of Junctophilin-2 with SK2 channel and Ryanodine Receptor Type 2 in Myocardium

Interactions of Junctophilin-2 with SK2 channel and Ryanodine Receptor Type 2 in Myocardium

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：llllljjjjjxxxxx
【摘 要】
：
Aim:Junctophilins (JPs) are main membrane-binding proteins that are associated with the functions of junctional membrane complexes (JMC).Small conductance Ca2+ activated K+ channels (SK) profiles the
【作 者】
：
樊红琨 罗天霞 郑春光 杨阳 涂会引 章茜 
【机 构】
：
河南省郑州市科学大道100号郑州大学基础医学院生理教研室,郑州市,450001
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
JP2 SK2 RyR2 cardiac myocyte 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Aim:Junctophilins (JPs) are main membrane-binding proteins that are associated with the functions of junctional membrane complexes (JMC).Small conductance Ca2+ activated K+ channels (SK) profiles the shape of the action potential of the cardiac myocytes.RyRs are an intracellular Ca2+ release channel existing in SR of eukaryotic cells.
其他文献
Contradictory role of apelin in vascular calcification
Apelin is a cardiovascular peptide with multiple functions regulating homeostasis of the circulatory system and is the endogenous ligand of angiotensin receptor AT1 (APJ).The role of apelin/APJ system
会议
vascular calcificationapelinAPJsmooth muscle cell
Flow-dependent Epigenetic Mechanism in Regulation of Vascular Endothelial Proliferation and Inflamma
Shear stress,the tangential component of the hemodynamic forces acting on the vascular wall,has been shown to play crucial roles in the regulation of vascular endothelial function,as well as the forma
会议
EndotheliumShear stressAtherosclerosisDNA methylationDNMT1
Cathepsin K effects Ischemia-Induced Neovascularization in old Mice
Cysteinyl cathepsins (Cats) have been implicated in the process of angiogenesis.we investigated the role of CatK in ischemia-induced neovascularization with a special focus on Notch1 activation in old
会议
Cathepsin KNeovascularizationIschemiaold
Endoplasmic reticulum oxidoreductin 1α mediates hepatic endoplasmic reticulum stress in homocysteine
Endoplasmic reticulum (ER) stress is emerging as an important modulator of different pathological process and as a mechanism contributing to homocysteine (Hcy)-induced hepar injury.However,the molecul
会议
endoplasmic reticulum stressendoplasmic reticulum oxidoreductin 1αhomocysteine
Foot shock potentiates blood coagulation system of rats
[Objective]To observe the influence of foot shock on blood coagulation system of rats.[Methods]Male Sprague Dawley(SD)rats were randomly divided into four groups: Control group(n=6),foot shock group(n
会议
Coagulation functionFoot shockOxidative stressRenal sympathetic nerve system
15-Lipoxygenase and 15-Hydroxyeicosatetraenoic Acid regulate intravascular thrombosis in pulmonary h
AIM:Pulmonary arterial hypertension (PAH) is a disease characterized by thickening of pulmonary artery walls,elevated pulmonary vascular resistance,pulmonary vascular thrombotic lesions and right-hear
会议
15-lipoxygenasepulmonary hypertensioncoagulationplatelet activation
Cartilage oligomeric matrix protein on the phenotype transformation of PASMCs via BMPRⅡ signaling pa
Rationale:Pulmonary arterial hypertension (PAH) is a malignant disease and the pathological mechanism is unclear.Pulmonary arterial remodeling is a major pathological change of PAH and Pulmonary arter
会议
cartilage oligomeric matrix proteinPASMCsphenotype transformationBMPRⅡ
Long-term exercise delays the development of hypertension by downregulating GRK2 and thus improving
Aims:Exercise training,a recommended nonpharmacological strategy for hypertensive patients,exerts beneficial effect on blood pressure modulation,but the underlying mechanisms remain elusive.Vascular i
会议
HypertensionGRK2Vascular insulin resistanceExercise
Vascular insulin resistance and underlying mechanisms in prehypertensive young SHRs
Aims:Vascular insulin resistance contributes to elevated peripheral vascular resistance and subsequent hypertension.Clinical observation has revealed that a low plasma adiponectin concentration is ass
会议
HypoadiponectinemiaAPPL1Vascular insulin resistancePrehypertensionEndotheliu
JNK信号通路在低剂量乙醇干预糖尿病大鼠心肌纤维化中的作用
目的：观察低剂量乙醇干预对糖尿病大鼠心肌纤维化的影响，分析糖尿病心肌纤维化与线粒体ALDH2 水平之间的关系，并探讨ALDH2 是否通过JNK 通路参与调节。方法：雄性SD 大鼠随机分成四组：正常对照组(Con)，糖尿病4 周组(DM 4w)，糖尿病8 周组(DM 8w)，乙醇+糖尿病8 周组(EtoH+DM 8w)。
会议
糖尿病大鼠心肌纤维化ALDH2JNK乙醇