Applications of cell-based therapy:from the research laboratory to pre clinical development to thera

• 作 者: ShellyHeimfeld;
• 机 构: International Society of Cellular Therapy (ISCT) Clinical Research Division Cellular Therapy and cGM
• 出 处: 第五届21世纪中美医学论坛(The 5th Sino-US Symposium on Medicine in the 2
• 发表日期: 2007年期

　　Application of cell-based therapy to the field of regenerative medicine is one of the most promising and exciting areas of biomedical research, an emerging clinical strategy that is based on the use of specific cell types to provide selective therapeutic benefit.Identification of new sources and types of stem cells, discovery of "additional/unex pected" differentiation pathways, along with major advances in purification, culture, and tissue engineering tech nologies are all contributing to an explosion of research publications, initiation of clinical trials, and tremendous public interest.Cell-based therapy is now being investigated in many different clinical settings, such as cancer, au toimmune diseases, immunotherapy, correction of genetic abnormalities, even for cardiac and nerve damage repair.However, the broad scope and remarkable potential of cellular therapy also presents many challenges that will need to be overcome before cell-based regenerative medicine can become the standard of care for a significant percentage of patients.