【摘 要】
：
C.elegans is a widespread model organism because of its invariant cell lineage among embryogenesis in normal individuals.Recently,biologists developed 3D ti
【机 构】
：
厦门大学数学科学学院概率统计系,福建厦门,361000香港中文大学理学院统计系
【出 处】
：
第七届全国生物信息学与系统生物学学术大会
论文部分内容阅读
C.elegans is a widespread model organism because of its invariant cell lineage among embryogenesis in normal individuals.Recently,biologists developed 3D time-lapse confocal laser microscope to take 3D movie of C.elegans embryogenesis.In order to make the data more vivid and intuitive,we draw binary tree graph to represent the cell lineage of C.elegans.Each node denotes one cell and the branch length is calculated as life time of corresponding mother cell.As we mentionedbefore,normal individuals usually have similar tree structures.However,with respect to mutants,they may have a large difference in tree structure compared with normal ones.Through studying the cell lineage tree distance,we can distinguish mutants from normal ones and hence infer gene function.
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