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  5. Analysis of Chemical Bioactivity through In Vitro Profiling using ToxCast and Tox21 High-Throughput

Analysis of Chemical Bioactivity through In Vitro Profiling using ToxCast and Tox21 High-Throughput

来源 :2015毒性测试替代方法与转化毒理学(国际)学术研讨会 | 被引量 : 0次 | 上传用户：xiaoxiaoxiaoren
【摘 要】
：
Safety assessment of drugs and environmental chemicals relies extensively on animal testing.However, the quantity of chemicals needing assessment and challenges of species extrapolation drive the deve
【作 者】
：
Keith W.Houck 
【机 构】
：
National Center for Computational Toxicology, US EPA;Research Triangle Park, North Carolina, USA
【出 处】
：
2015毒性测试替代方法与转化毒理学(国际)学术研讨会
【发表日期】
：
2015年5期
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　　Safety assessment of drugs and environmental chemicals relies extensively on animal testing.However, the quantity of chemicals needing assessment and challenges of species extrapolation drive the development of alternative approaches.The EPAs ToxCast and the multiagency Tox21 programs address this through use of an extensive in vitro screening program to generate data on a large library of important environmental chemicals.
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