Fucoidan对β淀粉样肽25-35和D-gal所致衰老小鼠学习记忆障碍的改善作用及机制研究

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  阿尔茨海默症(Alzheimer’s disease,AD)是一种进行性神经退行性疾病,临床表现为记忆和其他认知功能的丧失。现代医学研究表明,AD 发病主要与β-淀粉样蛋白(Aβ)在脑组织异常沉积导致脑内神经血管单元功能异常,从而进一步导致Aβ 清除障碍、胆碱能神经元受损、氧化应激、神经炎症反应或基因突变等因素有关。
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