Pathogen-expanded CD11b+ regulatory NKT cell feedback inhibits T cell proliferation via membrane-bou

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:man416784150
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Natural killer T cells (NKT cells) are not only the effector cells, but also regulator of immune response, which can either promote or suppress cellular immune response through production of different cytokines.However, the subsets of NKT cells with definite phenotype and regulatory function need to be further identified.Furthermore, the mechanisms for NKT cells to regulate immune response remain to be fully elucidated.Here we identified CD1 1b+ NKT cells as a new subset of regulatory NKT cells in the mouse models with infection.TCRβ+NK1.1 + NKT cells could be categorized to CD 1 1b+ and CD 1 1b subsets.
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