Anti-inflammatory Role of Bone Morphogenetic Protein 4 in Acute Airway Inflammation

来源 :The Third Internaitional Conference on Respiratory Diseases( | 被引量 : 0次 | 上传用户:dxy_10121012
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  Rationale Bone morphogenetic protein (BMP) 4, a member of TGF-β superfamily proteins, plays important roles in lung development and proximal-distal differentiation.It is unknown whether BMP4 participates in the process of airway innate immunity and bacterial clearance.Methods Acute lung inflammation in mice was induced by intranasal inhalation of 7.5 pg/mouse LPS.
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