Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via a calmodulin/Src-

来源 :首都医科大学2013年研究生学术论坛 | 被引量 : 0次 | 上传用户：xiehao2008

【摘要】

：

【作者】

：

Weiwei Yang Xue Wang Chunli Duan Lingling Lu Hui Yang

【出处】

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首都医科大学2013年研究生学术论坛

【发表日期】

：

2013年2期

【关键词】

：

alpha-synuclein (α-Syn) Parkinson's disease (PD) protein phosphatase 2A (PP

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　　Alpha-synuclein (α-Syn) is the principal protein component of Lewy bodies, a pathological hallmark of Parkinsons disease (PD).This protein may regulate protein phosphatase 2A (PP2A) activity, although the molecular mechanisms for α-Syn-mediated regulation of PP2A and the potential neuroprotective actions of PP2A against PD-associated pathology remain largely unexplored.

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Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via a calmodulin/Src-

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