Melatonin inhibits testosterone production via the GATA-4/SF-1 signaling pathway in leydig cells

• 作 者: QinFenju[1]TongJian[2]
• 机 构: School of Public Health, Soochow University, Suzhou 215021, China
• 出 处: 2015年中国中西医结合学会时间生物医学专业委员会学术研讨暨换届会议
• 发表日期: 2015年期

　　Melatonin has been reported of inhibitory effect on testosterone production.However,how this effect works remains largely unknown.The aim of the present study was to elucidate whether the GATA-4/SF-1 signaling pathway is involved the inhibitory effects of melatonin on testosterone production in both the TM3 Leydig cell line and in C57BL/6J mice.