论文部分内容阅读
核酸是一类生物大分子化合物，作为最主要的遗传物质它在生命活动过程起着至关重要的作用。精准的核酸测序有助于理解生理过程。在DNA 和RNA 中，选择性的切割特定的碱基对于确定碱基的序列提供了一个有效的途径。
利用过硫酸钾检测DNA和RNA中的鸟嘌呤
【摘 要】
：
核酸是一类生物大分子化合物，作为最主要的遗传物质它在生命活动过程起着至关重要的作用。精准的核酸测序有助于理解生理过程。在DNA 和RNA 中，选择性的切割特定的碱基对于确定碱基的序列提供了一个有效的途径。
【机 构】
：
武汉大学化学与分子科学学院 湖北省武汉市武昌区八一路299号,430072
【出 处】
：
中国化学会第十届全国化学生物学学术会议
【发表日期】
：
2017年10期
其他文献
Integration of metabolomics and transcriptomics reveals global responses to colloidal bismuth subcit
Colloidal Bismuth Subcitrate(CBS)has been widely used for the treatment of gastric ulcer and Helicobacter pylori(H.pylori)infection combined with andtibiotice and proton pump inhibitors in clinic.
G-四链体形成序列广泛存在于人类基因的调控区域,包括人端粒末端和原癌基因启动子区如c-kit、bcl-2 和c-myc 等[1],与癌细胞的凋亡和增殖息息相关。因此,G-四链体DNA 是发展抗癌药物的潜在靶标,受到国内外许多研究者的关注[2]。
1,2-Benzisoselenazol-3(2H)-one Derivatives:A Potential Broad-Spectrum Metallo-β-lactamase Inhibitors
The development of β-lactam antibiotics,such as penicillins,cephalosporins and carbapenems,has led to the availability of drugs to treat a wide range of Gram-positive and Gram-negative bacterial infec
循环肿瘤细胞(CTCs,Circulating Tumor Cells)是脱离原来病变器官,通过外周血液循环转移到血液、骨髓、淋巴结或其他器官的肿瘤细胞。
Autofluorescence-free targeted tumor imaging based on aptamer-functionalized persistent luminescence
Optical bioimaging is an indispensable tool in modern biology and medicine,but the technique is susceptible to autofluorescence interference.
Electrochemical DNA sensor with three-dimensional graphene modified electrode for staphylococcus aur
Electrochemical DNA sensing for nuc ssDNA sequence originated from Staphylococcus aureus was reported with an electrodeposited three-dimensional(3D)graphene(GR)modified electrode.
Existence of N7-methylguanosine modification in internal mRNA determined by differential enzyme trea
N7-methylguanosine(m7G)modification generally occurs at the 5-end of mRNA of eukaryotes and plays critical roles in mRNA biogenesis and stability [1].
We investigated a conjugated polyelectrolyte(CPE)containing terthiophene units in its backbone PPET3-N+for PDT treatment under white light irradiation.
Conjugated polymers(CPs)has caused wide public concern due to its potential application in many fields over recent years.
A Novel Nitroreductase-enhanced MRI Contrast Agent and its Potential Application in Bacterial Imagin
Nitroreductases(NTRs)are present in a wide range of bacterial genera and,to a lesser extent,in eukaryotes hypoxic tumour cells and tumorous tissues,which makes it an appropriate biomarker for an imagi