Intravitreal administration of bevacizumab in the treatment of choroidal metastasis in a patient wit

来源 :第九届中国肿瘤学术大会暨第十五届海峡两岸肿瘤学术大会 | 被引量 : 0次 | 上传用户:guobin_tj
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Choroidal metastasis is uncommon and usually identified in a relatively advanced cancer status.The median survival after diagnosing choroid metastasis in lung cancer patients was only 1.9 months.Once failed to systemic treatment,there was no effective local treatment for saving visual acuity.The off-label use of intravitreal bevacizumab was popular in treating VEGF-mediated chorioretinal diseases worldwide.We here demonstrate a dramatic and durable response to intravitreal bevacizumab.Unlike the previous similar reports,our patient had failed both first-and second-line therapies.
其他文献
目的:18F-FMISO是目前应用最多的PET乏氧显像剂,但其对三阴型乳腺癌(即雌激素受体、孕激素受体和人表皮生长因子受体2表达均为阴性)乏氧微环境的检测能力尚无研究资料。本研究将讨论18F-FMISO能否探测三阴型乳腺癌的乏氧状态。方法:三阴型乳腺癌细胞MDA-MB-231种植于裸鼠右前肢建模。对荷瘤裸鼠模型注射18F-FMISO和18F-FDG后分别行Micro-PET显像,并比较二者代谢的
目的:探讨血小板型12-脂氧合酶(platelettype12-lipoxygenase,p12-LOX)选择性抑制剂黄芩素(baicalein,BAI)对胃癌MKN-28细胞增殖和迁移的影响及机制.方法:应用RT-PCR检测胃癌MKN-28细胞和正常胃黏膜GES-1细胞中p12-LOX的mRNA表达;应用MTT法检测不同浓度的BAI处理MKN-28细胞后的增殖情况;划痕愈合实验和Transw
目的:肝细胞癌(Hepatocellularcarcinoma,HCC)是世界第五大常见的恶性肿瘤,每年大约有50万患者死亡,病死率居世界第三。全世界约80%的肝癌病例存在乙肝病毒感染。乙型肝炎病毒(HepatitisvirusB,HBV)DNA由于存在HBV聚合酶的校正缺陷而容易发生突变,本研究评价了HBVPrecore/Core区基因突变在乙型肝炎相关的原发性肝癌患者预后中的价值。
会议
会议
Angiogenesis,the process of new blood vessel formation,is important in wound healing,inflammation,tumorigenesis and metastases.During this process,it is a critical step of the loosening of cellular in
会议
BACKGROUND: In this study,we investigated the efficacy of continuous epidermal growth factor receptor(EGFR)tyrosine kinase inhibitors(TKIs)administration in lung adenocarcinoma patients harboring favo
会议
会议
会议