Diversity of Cyclic-di-Nucleotide Binding Proteins and Their Roles in Bacterial Pathogenicity

• 作 者: Shan-Ho Chou
• 机 构: InstituteofBiochemistry,NationalChungHsingUniversity,Taichung,40227,Taiwan
• 出 处: The 4th International Conference on Biotic Plant Interaction
• 发表日期: 2015年8期

Over the last ten years or so, cyclic nucleotides, such as c-di-GMP, c-di-AMP, or cGMP have emerged as important second messengers in bacterial signal transduction and regulation.1, 2 A rapidly expanding body of work has described the multiple biological functions mediated by c-di-GMP and c-di-AMP in bacteria, as well as their actions as activators for the STING protein of the mammalian innate immune response.It is very likely that further functions will be discovered.