Lysophosphatidic acid inhibits the role of hydrogen peroxide-induced apoptosis of bone marrow mesenc

来源 :2013中国心脏大会(CHC) | 被引量 : 0次 | 上传用户：yangxinquan911

【摘要】

：

【作者】

：

Xianyun Wang Xuesong Fan Fang Wang Lin Cai Jinjing Yang Xiangfeng Cong Xi Chen

【机构】

：

State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,National Center for Cardiovascular Dis

【出处】

：

2013中国心脏大会(CHC)

【发表日期】

：

2013年2期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Objective Stem cell transplantation is becoming a new strategy of ischemic heart disease treatment in recent years.The survival rate of transplantation stem cell is the key problem to limit its curative effect We Use hydrogen peroxide (H2O2) induced rat bone marrow mesenchymal stem cells (BMSC) apoptosis to build cell oxidative stress damage model for exploring anti-apoptosis role of a kind of endogenous bioactive molecules-hemolysis phosphatidic acid (LPA).

其他文献

Overexpressing Cellular repressor of E1Astimulated genes promote hypoxia-induced VEGF paracrine via

Background Hypoxia inducible factor-1α (HIF-1α) is the key transcription regulator for multiple angiogenic factors, including vascular endothelial growth factor (VEGF).

会议

No association between PON1 gene single nucleotide polymorphisms and clopidogrel resistance in Chine

Background Clopidogrel requires bioactivation in vivo to convert the pro-drug into its active metabolite to show its antiplatelet effects.The variability in the clinical response to clopidogrel treatm

会议

Advanced Glycation End Products induces apoptosis and shorts telomere length in human adipose tissue

Objective To investigate the effects of advanced glycation end products (AGEs) on apoptosis and telomere length of human adipose tissue-derived stem cells (ADSCs) and the related molecular mechanism.

会议

Effects of advanced glycation end products on function and angiogenesis of adipose tissue-derived st

Objective To investigate the effects ofNε-(carboxymethyl) Lysine albumin (CMLs), a primary advanced glycation end products isoform in diabetic body, on function and angiogenesis of adipose tissue-deri

会议

Gene-gene interactions among PPAR α / 6 / γ polymorphism for lipid accumulation product in Chinese H

Objective This study aimed to investigate the association between 10 single-nucleotide polymorphism (SNPs) in the peroxisome proliferator-activated receptors (PPARs) and lipid accumulation product (LA

会议

The expression of cystathionine gamma-Iyase/hydrogen sulfide pathway in CVB3-induced myocarditis and

Objective This study amied to investigate the expression of cystathionine ga mma-lyase/hydrogen sulfide pathway in CVB3-induced myocarditis and the protectiove role of hudrogen sulfide.

会议

Ischemia/reperfusion-induced MKP-3 impairs endothelial NO formation via inactivation of ERK1/2 pathw

Mitogen-activated protein kinase phosphatases (MKPs) are a family of dual-specificity phosphatases.Endothelial cells express multiple MKP family members, such as MKP-3.

会议

Panax notoginseng saponins ameliorates coxsackievirus B3-induced myocarditis by activating cystathio

Objective This study amied to investigate whether or not panax notoginseng saponins (PNS) ameliorates coxsackievirus B3-induced myocardtis by activating cystathionine ga mma-lyase (CSE)/hydrogen sulfi

会议

Angiotensin Ⅱ-Induced cardiomyocyte hypertrophy is attenuated by neuregulin receptor degradation Pro

Objective Recent studies indicate ubiquitin-proteasome system particularly the E3 ubiquitin ligase plays a key role in cardiac hypertrophy.We have previously shown that overexpression of Neuregulin re

会议

Loss of cardioprotection by sevoflurane postconditioning against myocardial ischemia-reperfusion inj

Background Sevoflurane postconditioning protects young hearts against ischemia-reperfusion injury.It is unknown whether the infarctlimiting effect is also maintained in aged cohorts, and whether there

会议

Lysophosphatidic acid inhibits the role of hydrogen peroxide-induced apoptosis of bone marrow mesenc

其他学术论文