18F-FDG PET-CT功能影像引导下鼻咽癌同步加速生物调强放疗疗效分析

来源 :中华医学会第十二次全国放射肿瘤学治疗学学术会议 | 被引量 : 0次 | 上传用户：sony360

【摘要】

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【作者】

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刘科朱苏雨刘媛媛吴峥邓俊刘国才

【机构】

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湖南省肿瘤医院淋巴瘤腹部放疗科,湖南省肿瘤医院生物靶向调强放射研究室湖南大学电气工程学院

【出处】

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中华医学会第十二次全国放射肿瘤学治疗学学术会议

【发表日期】

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2015年9期

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目的局部复发是鼻咽癌治疗过程中面临的主要问题之一.即使运用调强放疗联合同步化疗,局部晚期鼻咽癌的局部复发率仍然达20-30％.18F-FDG PET-CT显像能反应肿瘤内部的生物学信息,有研究运用18F-FDG PET-CT引导进行生物调强放疗以改善鼻咽癌治疗效果,但各研究病例数较少、随访时间较短且主要为其他头颈部鳞癌,因此对鼻咽癌的治疗效果需要进一步探讨.还有研究显示,运用同步加速调强放疗(simultaneous modulated and accelerated radiation therapy,SMART)有可能改善鼻咽癌的治疗效果.从2007年开始,我院开始使用结合上述两种技术的同步加速生物调强放疗(SMABRT)治疗鼻咽癌.本研究拟通过分析这部分病人的疗效及晚期反应,来探讨同步加速生物调强放疗治疗鼻咽癌的疗效及安全性.

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18F-FDG PET-CT功能影像引导下鼻咽癌同步加速生物调强放疗疗效分析

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