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目的探讨Rasmussen脑炎临床特点以及外科治疗。方法回顾性分析2006年10月～2008年11月期间我科收治的5例行半球切除治疗的Rasmussen脑炎病例。结果5例均行半球切除术,3例左侧,2例右侧。无手术死亡率及严重并发症,术后病理诊断符合Rasmussen脑炎改变,随访6个月到24个月,所有病人发作均消失。结论Rasmussen脑炎是一种进展性脑炎伴偏瘫及顽固性癫痫疾病,尽早行半球切除是治疗这种疾病的惟一可行的办法。
Objective To investigate the clinical features and surgical treatment of Rasmussen encephalitis. Methods Retrospective analysis of 5 cases of Rasmussen encephalitis treated by hemisphere excision in our department from October 2006 to November 2008 was retrospectively analyzed. Results All the patients underwent hemispheric resection in 5 cases, left side in 3 cases and right side in 2 cases. No surgical mortality and serious complications, postoperative pathological diagnosis consistent with changes in Rasmussen encephalitis, followed up for 6 months to 24 months, all patients were seizures disappeared. Conclusions Rasmussen encephalitis is a progressive encephalitis complicated with hemiplegia and intractable epilepsy. As soon as possible, hemispherectomy is the only feasible way to treat this disease.