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  5. 肠道缺血再灌注在出血坏死性胰腺炎中作用研究

肠道缺血再灌注在出血坏死性胰腺炎中作用研究

来源 :中华医学会第十七届全国外科学学术会议 | 被引量 : 0次 | 上传用户：ligang_nc2
【摘 要】
：
目的 探讨肠道缺血再灌注损伤(IIR)在缺血坏死性胰腺炎(HNP)早期炎性反应发生发展中作用及机制.方法 将48只实验大鼠分为假手术组,急性水肿型胰腺炎组,水肿型胰腺炎合并缺血再灌组和出血坏死性胰腺炎组.于术后lh、2h、3h、6h分别检测观察小肠系膜微循环红细胞流速(EV)、功能毛细血管密度(FCD)及白细胞粘附数(LA);测定血清TNF-α及IL-6水平;SABC及Western-blot检测
【作 者】
：
赵刚 
【机 构】
：
武汉协和医院胰腺外科 430022
【出 处】
：
中华医学会第十七届全国外科学学术会议
【发表日期】
：
2013年4期
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目的 探讨肠道缺血再灌注损伤(IIR)在缺血坏死性胰腺炎(HNP)早期炎性反应发生发展中作用及机制.方法 将48只实验大鼠分为假手术组,急性水肿型胰腺炎组,水肿型胰腺炎合并缺血再灌组和出血坏死性胰腺炎组.于术后lh、2h、3h、6h分别检测观察小肠系膜微循环红细胞流速(EV)、功能毛细血管密度(FCD)及白细胞粘附数(LA);测定血清TNF-α及IL-6水平;SABC及Western-blot检测VCAM-1表达.
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