The SERM Regulation of Proliferation and Steroid Receptor Expression in the Cultures of Human Mammar

来源 :2011第四届世界癌症大会暨乳腺癌峰会 | 被引量 : 0次 | 上传用户：Wangqiling1116

【摘要】

：

【作者】

：

Pirkko H(a)rk(o)nen Natalija Eigeliéne Lauri Kangas Risto Erkkola

【机构】

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Head of Institute of Biomedicine University of Turku Finland

【出处】

：

2011第四届世界癌症大会暨乳腺癌峰会

【发表日期】

：

2011年3期

【关键词】

：

human breast cultures estrogen steroid receptors SERM proliferation apoptosis

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　　1.The development and function of human mammary gland is regulated by steroid hormones.Estrogen has a master role in mammary growth and function, followed by specific actions of progesterone and androgens.The receptors for steroid hormones are located in only a proportion of mammary epithelial cells and their effects are largely mediated by autocrine and paracrine mechanisms by steroid induced growth factors and cytokines.Based on other species the effects of estrogen and progesterone in breast are considered.

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The SERM Regulation of Proliferation and Steroid Receptor Expression in the Cultures of Human Mammar

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