Aryl(fluoroalkyl)sulfonium Salts From Fluoroalkylation to Arylation

来源 :中国化学会第十四届全国氟化学会议 | 被引量 : 0次 | 上传用户:qinghuawuqiong
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  Arylation of arylboronic acids by aryl(fluoroalky.1)sulfonium salts was successfully implemented in the presence of Pd-catalysts,which provided the corresponding diaryl compounds in good to high yields.[Ar2SR][OTf](R =fluoroalkyl) were also effective cross-coupling partners in Pd-catalyzed Mizoroki-Heck-type reaction with alkenes.The functionalization of conjugated and unconjugated alkenes by[Ar2SR][OTf]in the presence of 10 mol% Pd[P(t-Bu)3]2 and TsOH at room temperature afforded the arylation products in good to high yields.The reactions verify that the S-Ar bonds of[Ar2SR][OTf]can be readily cleaved by palladium complex.These protocols demonstrate a new class of cross-coupling participants for Suzuki-Miyaura and Mizoroki-Heck-type reactions and gain very important insights into the reactivity of arylsulfonium salts either with or without fluorine-containing alkyl groups.
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