Change-Point Modeling of Copy Number Aberrations in Cancer Genomics

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：yanyuhan66

【摘要】

：

In normal somatic cells,there are two copies of every chromosome.In cancer cells,copy number aberration(CNA)is an important type of genomic change,where large duplications and deletions lead to copy n

【作者】

：

Yuchao Jiang Hao Chen Nancy R Zhang

【机构】

：

Genomics and Computational Biology Graduate Program,Perelman School of Medicine,University of Pennsy

【出处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

change-point copy number aberrations cancer genomics normalization segmentation

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Change-Point Modeling of Copy Number Aberrations in Cancer Genomics

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