Inhibition of Wnt/β-catenin signaling promotes engraftment of mesenchymal stem cells to repair lung

• 作 者: ZhaoruiSun;ZhizhouYang;HongmeiLiu;DanbingShao;BaodiSun;WeiZhang;YiRen;JinfengLin;MinXu;ShinanNie;
• 机 构: Department of Emergency, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, PR
• 出 处: 2014北京协和急诊医学国际高峰论坛
• 发表日期: 2014年期

　　We sought to explore the treatment effects and the repair mechanisms of bone marrow derived mesenchymal stem cells (MSCs) during HCl-induced acute lung injury (ALI).MSCs were delivered through the tail veins of rats 24h after intraperitoneally injection of paraquat.The results showed that MSCs did not ameliorate the histopathologic changes of ALI and pulmonary fibrosis.