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本文基于流行病学探索病因的基本条件,通过六个方面的研究,比较系统地分析探讨了血吸虫病与大肠癌的关系。结果表明:血吸虫病流行严重地区的大肠癌死亡率较非流行及轻流行区为高;曾经感染过血吸虫人群的大肠癌死亡率显著高于未感染血吸虫的人群;病例一对照研究经单因素分析,都显示出大肠癌病例中有血吸虫病史的比例明显高于对照者;确诊血吸虫病年限与相对危险度呈平行关系;晚期血吸虫病对大肠癌死亡有更高的危险性。这些结果与基本消灭血吸虫病后大肠癌年龄别死亡率和平均死亡年龄的变化,均说明了血吸虫病与大肠癌之间存在着关联。
This article is based on epidemiological exploration of the basic conditions of the cause, through six aspects of the study, a more systematic analysis of the relationship between schistosomiasis and colorectal cancer. The results showed that the mortality rate of colorectal cancer was higher in areas with severe schistosomiasis than in non-prevalent and light endemic areas. The mortality rate of colorectal cancer in people who had been infected with schistosomiasis was significantly higher than that of people without schistosomiasis; the case-control study was analyzed by univariate analysis. All showed that the proportion of schistosomiasis patients with colorectal cancer was significantly higher than that of the controls; the duration of confirmed schistosomiasis was parallel to the relative risk; advanced schistosomiasis had a higher risk of death from colorectal cancer. These results and the basic eradication of schistosomiasis after age-related mortality and mean death age of colorectal cancer, both show that there is a link between schistosomiasis and colorectal cancer.