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Purpose: Maxillary defect caused by tumor,trauma,and congenital deformity shade great influence on patients function and aesthetics,affecting their quality of life.As the development of Computer-Assisted Surgery(CAS)technique became widely applied in Oral-Maxillofacial Surgery,the reconstruction of maxillary defect is heading for a more precise and individualize criteria.This study plan to compare different CAS method applied in maxillary reconstruction,in order to draw a workflow for each method,evaluate their advantages and disadvantages and their clinical application value.