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There are obvious disadvantages in the ASME pressure vessel code which is used to calculate the fatigue life of cylinders by adopting an equivalent strain method, because it cannot take account of the multiaxial non-proportional loading effect.This paper studies the multiaxial low cycle fatigue life of composite cylinders by adopting the corrected Brown-Miller algorithm as well as the effect of autofrettage pressure, metal liner thickness and each ply thickness on the composite cylinders' fatigue life and gives a solution for increasing the composite cylinders' fatigue life.