SAD-A controls incretin response in islet β-cells as a novel effector of mTORC1 signaling

来源 :中华医学会糖尿病学分会第十八次全国学术会议 | 被引量 : 0次 | 上传用户:finallove
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Type 2 diabetes(T2DM)is characterized by insulin resistance and β-cell failure which leads to depletion of islet β-cell mass.These defects can be mitigated in part by treatment of T2DM patients with GLP-1,an incretin hormone which potentiates glucosestimulated insulin secretion and increases islet β-cell mass.
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