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A 60-day feeding trial was conducted to determine the effects of palm oil blended with oxidized fish oil and non-oxidized fish oil on growth performances, hematology and non-specific immune in juvenile Japanese sea bass Lateolabrax maculatus.Juvenile Japanese sea bass (initial weight 1.73 ±0.01g) were fed seven experimental diets containing 10% of diet lipid in forms of palm oil (10P), fish oil (10F), fish oil blended palm oil at ratio of 6∶4 (6F4P), fish oil blended palm oil at ratio of 4∶6 (4F6P), oxidized fish oil (10OF), oxidized fish oil blended palm oil at ratio of 6∶4 (6OF4P) and oxidized fish oil blended palm oil at ratio of 4∶6 (4OF6P).No significant effects were observed on Survival, feed conversion ratio (FCR),condition factor (CF), and hematocrit (Hct) after feeding with experimental diets for 60 days.The relatively higher specific growth rate (SGR), hemoglobin (Hb), serum glucose (Glu), and red blood cell (RBC) were all observed in 6F4P, and a slightly promotion trend was also found in oxidized groups of these parameters.Furthermore, both palm oil and oxidized fish oil acted as a negative effect on serum lysozyme activity (P<0.05).