胞外ADP及其受体对巨噬细胞介导的抗菌免疫功能的调控作用和机制研究

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：kf_haiyang

【摘要】

：

背景：近年来的研究发现，核苷酸作为一种危险信号分子对激活巨噬细胞、调节炎症具有十分重要的作用。而对胞外核苷酸ADP在细菌感染过程中的功能及作用机制尚未有详细报道。方法：为此本课题首先建立了小鼠体内、外的细菌感染模型，并对细菌感染过程中胞外ADP的释放、受体表达以及ADP的抗菌作用进行了初步评价。

【作者】

：

张晓雨邹军燕钱雅敏秦居亮任华杜冰钱旻

【机构】

：

华东师范大学生命科学学院 200241

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

ADP 嘌呤受体巨噬细胞 MCP-1 细胞迁移

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