Differential expression of long non-coding RNA in lung tissues from chronic cigarette smoke induced

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:df0225
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  目的 Chronic Obstructive Lung Disease(COPD)is a global health problem.It has caused severe mortality and disease burden allover the world.Cigarette smoke(CS)is a major etiological factor of COPD.Emerging evidence have demonstrated that aberrantexpression of lncRNAs is associated with various diseases.In this study,we used CS-induced COPD mouse models to investigatethe expression profile of lncRNAs,which might be associate with the physiopathology of COPD.
其他文献
目的 探讨对全身麻醉(全麻)术后出现肺不张患者的诊疗、护理进行探讨.方法 9例全麻术后肺不张患者,对其诊疗、护理方法及治疗效果进行分析.结果 9例患者均行肺不张经纤维支气管镜检查,结果显示:血性分泌物3例,气管分泌物6例,患者均接受灌洗吸痰、抗生素等治疗,复张.5例患者仅灌洗1次,复张;灌洗2次及以上复张者3例,3例行面罩加压鼓肺,除1例死于术后大出血,其余7例均治愈.结论 全麻术后患者出现肺不张
目的 Cigarette smoking is the principal environmental risk factor for COPD and EGLN2(egl-9 family hypoxia-inducible factor 2)isrelated to smoking behavior.We aimed to evaluate the role of single nucleot
目的 The mortality of acute respiratory distress syndrome(ARDS)is dramatically high and there is no proven pharmacologicintervention now.Mechanical ventilation is one of the most important auxiliary tre
目的 To explore the impact of chronic obstructive pulmonary disease(COPD)on renal vessel function by comparing level ofserum renal vessel damage biomarkers-in patients with and without COPD.方法 Eighty tw
目的 应用ROC曲线评价支气管舒张试验对哮喘的诊断价值 方法 收集2014年1月至2015年1月期间在中南大学湘雅医院肺功能室进行支气管舒张试验检查的805例患者的临床资料和肺功能数据,临床随访一月,以医生最终诊断结果为金标准,分为哮喘组和非哮喘组。
目的 To investigate the radiotherapy effect of whole course nursing intervention for patients with NPC during radiotherapy.方法 whole course nursing intervention was performed for 42 patients with nasopha
目的 Malignant pleural effusion(MPE)is associated with a poor prognosis in lung cancer.Currently,no effective cure exists forMPE.Chloroquine(CQ)has been demonstrated to induce vascular normalization and
目的 Combined pulmonary fibrosis and emphysema(CPFE)syndrome is characterized by simultaneously occurrence of lower lobefibrosis and upper lobe emphysema which could be identified in some patient with c
目的 研究呼出气一氧化氮水平(fractional exhaled nitric oxide,FeNO)与气道反应性的相关性。方法 收集在中南大学湘雅医院完成FeNO检测、肺通气功能检查及支气管激发试验的患者资料;以PD20-FEV1衡量气道高反应性(airwayhyperreactivity,AHR)程度;对FeNO与AHR程度进行相关性分析。
目的 Toll-like receptor-4(TLR4)signaling has been implicated in innate immunity and acute inflammation following acutelung injury(ALI).As such,modulating inflammatory response through TLR4 represents an