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  5. Liver proteomic response to hypertriglyceridemia in human-apolipoproteinC-Ⅲ transgenic mice

Liver proteomic response to hypertriglyceridemia in human-apolipoproteinC-Ⅲ transgenic mice

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：wwwygtwww
【摘 要】
：
Aim: Hypertriglyceridemia (HTG) induced by over-expression of humanapolipoproteinC-Ⅲ (HuApoC-Ⅲ) was reported to disturb hepatocyte bioenergetics in transgenic mice presenting higher liver oxygen consu
【作 者】
：
Francis SLUSE Gregory EHX Stephanie GERIN 
【机 构】
：
Laboratory of Bioenergetics, University of Liege, Liege 4000, Belgium
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
hypertriglyceridemia proteomics liver mitochondria 
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Aim: Hypertriglyceridemia (HTG) induced by over-expression of humanapolipoproteinC-Ⅲ (HuApoC-Ⅲ) was reported to disturb hepatocyte bioenergetics in transgenic mice presenting higher liver oxygen consumption and body metabolic rate.These metabolic modifications remained poorly understood.In the present work we studied global proteomic response of HuApoC-Ⅲ mouse hepatocyte to HTG.
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