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How to prevent gastric cancer occurence and metastasis is a great challenge.Current study shows that gastric cancer(GC)is one kind of stem cell disease,which has a great influence on tumor initiation and metastatic behavior.Gastrc cancer stem cell(CSC)-focused therapy is destined to be one of the most promising paths in anticancer strategies.Herein,we report that branched gold nanostars(GNSs)are chosen as potential photothermal therapy(PTT)agents due to their excellent photothermal conversion efficiency in the near-infrared window and photoacoustic(PA)properties.