【摘 要】
：
Objective To observe the changes of SPARC expression and intervention effect of fasudil in experimental mice induced by bleomycin, so as to discuss the action mechanism of SPARC in pulmonary fibrosis.
【机 构】
：
Diseases of the Respiratory System Research Laboratory of the First Affiliated Hospital of Fujian Me
论文部分内容阅读
Objective To observe the changes of SPARC expression and intervention effect of fasudil in experimental mice induced by bleomycin, so as to discuss the action mechanism of SPARC in pulmonary fibrosis.
其他文献
The diagnosis of diffuse malignant pleural mesothelioma should always be based on adequate biopsy specimens for accurate classification of pathologic diagnosis and the sarcomatoid mesothelioma provide
Background In China, ＞50％ of the adult male population smokes, and the prevalence of COPD is rising.Medical care is not uniform in China, with wide variations in physician training and availability of
Background Richostatin A (TSA) is a nonisoform selective HDAC inhibitor, which can regulate gene expression through modulation of the status of acetylation of histone and non-histone, thus affecting c
Background COPD is considered to be a multi-component disease, and depression is one of the major comorbidities in COPD patients.The Gold 2011 for managing COPD highlight the importance of being aware
Background Diffuse panbronchiolitis (DPB), a chronic inflammatory disease of the airway, is treated with macrolide antibiotics.Therapeutic effects are currently assessed by improvements seen in comput
A 60-year-old woman admitted due to persistent cough associated with minimal expectoration for twenty days.A chest X-ray showed interstitial pneumonitis and bilateral infiltrate in the middle and lowe
Aim To investigate the factors affecting blood pressure of pre-and postmenopausal women with obstructive sleep apnea syndrome (OSAS).Methods A retrospective study including 207 women patients from 200
Reported here is a case of a 32-year-old Chinese female infected by sparganum mansoni, a kind of tapeworm, showing migratory path shadows in both lungs.She complained of intermittent cough and blood s
Background Generally, chronic obstructive pulmonary disease (COPD) responds poorly to treatment of bronchodilator and corticosteroids whereas small proportions present good effect based on many clinic
Objective To study whether the acute exposure to PM2.5 aggravates the airway injury in COPD rodents, and explore the protective effect of N-acetylcysteine in airway inflammation caused by PM2.5.Method