Ulinastatin improved cardiac dysfunction after cardiac arrest in New Zealand rabbits

• 作 者: HuChun-lin[1]LiHui[1]XiaJin-ming[1]LiXin[1]ZengXiao-yun[1]ZhanHong[1]JingXiao-li[1]GangDai[2]
• 机 构: Department of Emergency Medicine,the First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 5
• 出 处: 首届中山国际急诊与灾难医学论坛
• 发表日期: 2012年期

　　Objective The present study was designed to evaluate the effects of ulinastatin (UTI) on cardiac dysfunction after cardiopulmonary resuscitation (CPR).Methods A total of 48 healthy adult male New Zealand rabbits were untreated for 8 minutes after the induction of ventricular fibrillation (VF) by an external transthoracic alternating current and then treated by CPR.These rabbits were then randomly divided into the Control and UTI groups after the return of spontaneous circulation (ROSC) and were observed for 8 hours after the ROSC.