Hypoxia-induced pulmonary vascular adventitia fibroblast proliferation requires JNK-mediated Elk-1-d

• 作 者: 朱大岭;王晓艳;张莉;陈明刚;刘玉梅;邢妍;
• 机 构: 哈尔滨医科大学大庆校区,大庆 163319
• 出 处: 中国生理学会第24届全国会员代表大会暨生理学学术大会
• 发表日期: 2014年期

　　Background – 15-lipoxygenase (15-LO) induced vascular adventitia fibrosis,while its effect on pulmonary adventitial fibroblast (PAF) proliferation was unclear.The aim of the present study was intent to exploit the roles of 15-LO in modulation of PAF proliferation,and further reveal the potential mechanisms.