论文部分内容阅读
Objective The prognostic and predictive relevance of acquired trisomy 21 (+21) in acute leukemia are controversial.In order to assess the biological and clinical features of +21 as a sole acquired karyotypic abnormality, the present study retrospectively analyzed hematological patients with acquired +21.Method We retrospectively study the cytogenetic of hematological patients registered on Institutional Cytogenetic Laboratory in our hospital from January 1996 to June 2014.Patients who had +21 as a sole abnormality were further reviewed for clinical presentation, immunophenotype, treatment and clinical outcome.