Electrochemical study and application on rutin at chitosan/graphene films modified glassy carbon ele

• 作 者: JingAn[1]Ying-YanBi[1]Chun-XiaYang[1]Fang-DiHu[1]Chun-MingWang[2]
• 机 构: School of Pharmacy, Lanzhou University, Lanzhou 730000, China
• 出 处: 第一届当归国际学术研讨会
• 发表日期: 2014年期

　　Graphene (G) was dispersed into 0.5% chitosan (Chit) solution, then the composite films were coated on glassy carbon electrode (GCE), the electrochemical behavior of rutin on a Chit/G modified GCE was investigated and the electrochemical parameters of rutin were calculated.Rutin effectively accumulated on the Chit/G/GCE and caused a pair of redox peaks at around 408 mV and 482 mV (vs.SCE) in 0.1 M phosphate buffer solution (pH 4.0).Under optimized conditions, the anodic peak current was linear to the rutin concentration in the range of 5 × 10-7-1.04 × 10-5 M.The regression equation was: y=9.9219x-0.0025, r=0.9958.The proposed method was successfully used for the determination of rutin content in tablet samples with satisfactory results.