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As a highly malignant tumor, salivary gland adenoid cystic carcinoma (ACC)accounts for nearly 10% of all the epithelial salivary tumors and with a low 5-year survival rate less than 20% in highly metastatic patients.Pim-1 is an effective oncogene and is proved to phosphorylate a series of substrates to exert its function and play important role in many malignancies.