烟酰胺磷酸核糖转移酶基因表达下调对动脉粥样硬化的影响及其机制

来源 :中华医学会糖尿病学分会第十八次全国学术会议 | 被引量 : 0次 | 上传用户：kaokao514

【摘要】

：

目的近来研究发现,烟酰胺磷酸核糖转移酶(NAMPT)能够促进胆固醇的累积以及促进巨噬细胞泡沫细胞化的形成等.然而,NAMPT对动脉粥样硬化的影响及其机制尚不完全明确.因此,本研究拟探讨NAMPT基因抑制对高脂饮食诱导的野生C57及ApoE-/-小鼠胰岛素抵抗和动脉粥样硬化的影响及其相关分子机制.

【作者】

：

李敏燕王葱李伶杨刚毅

【机构】

：

重庆医科大学检验医学院临床生化教研室和教育部实验诊断学重庆医科大学附属第二医院内分泌科

【出处】

：

中华医学会糖尿病学分会第十八次全国学术会议

【发表日期】

：

2014年5期

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