HBV感染是肝细胞癌(HCC)发生的重要原因.但长期以来有两个现象令人困惑：同样是感染乙肝病毒,20％左右的人发病年龄低于30岁,40％以上的HBV携带者发病年龄大于70岁或终生不发生HCC.其次,HCC发病具有明显的家族聚集性,在同一家庭中HCC发病年龄常常比较接近.较之晚发肝癌,早发肝癌起病更为隐匿,不容易发现,而且恶性程度更高,预后更差,研究早发肝癌的发病机制对于预防和治疗早发肝癌意义重大.
Tumors of skin and subcutaneous tissues are the most frequently recorded tumors in farm animal species.In small ruminants squamous cell carcinomas and melanomas occur more frequently in body areas poo
Chemoprevention,a promising strategy to prevent cancer,is defined as the use of natural dietary compounds and/or synthetic substances to block,inhibit,reverse,or retard the process of carcinogenesis.
It is of most importance to decipher the role of environmental pollutants in the chronic carcinogenesis of human breast epithelia and their contribution in the development of this cancer.
Ovarian cancer is consistently one of the leading causes of cancer related mortality in the world.This unacceptably low survival rate is due to the metastasis and treatment failure.
In this study,reverse-transcription polymerase chain reaction (RT-PCR) was used to examine histamine-N-methyltransferase (HNMT) expression in 50 randomly selected human breast cancer samples and to co
Nanotechnology is a kind of novel technologies that provides a flexible platform for the development of effective therapeutic nanomaterials.These nanometerials can provoke a desired response in a biol
Daiichi Sankyo is a pharmaceutical company which develops innovative drugs for patients in serious diseases.Oncology is one of the focused therapeutic areas and currently 21 projects are under clinica
The preparation and cellular action of drug-delivery systems (DDS) are normally based on threedifferent processes.First the loading of the system with the therapeutic molecule that needs a coherent de
The human cancerous inhibitor ofPP2A (CIP2A) is regarded as a novel target for cancer therapy as its overexpression in 65% to 90% of tissues in almost all studied human cancers correlates with cancer