Upconversion luminescence of lanthanides doped fluorapatite for labeling and tracking bone marrow me

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户:xtb0909
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  Upconversion luminescent nanoparticles are becoming more widely used as imaging contrast agents, due to their high resolution and penetration depth, and avoidance of tissue auto-fluorescence and photodamage to cells. Here, we prepared upconversion fluorescent nanocrystals from rare-earth Yb3+ and Ho3+ co-doped fluorapatite (FA∶Yb3+/Ho3+) suitable for long-term tracking and monitoring cartilage development (chondrogenesis) in bone marrow mesenchymal stem cells (BMSCs) in vitro and in vivo.
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